Paris-based Jeito Capital, a PE fund centered on biopharma innovation, has furthered its place as a participant in world healthcare funding with two main contributions to clinical-stage biotech corporations Aviceda Therapeutics and XyloCor Therapeutics – totalling over €264 million.
Jeito’s present portfolio providing is valued at €534 million, with a deal with a patient-focused method and on financing the event and progress of “ground-breaking” medical innovation.
Jeito just lately participated within the upsized €199.6 million Collection C financing spherical for Aviceda Therapeutics, the financing spherical was co-led by Omega Funds and TCGX, with participation from Enavate Sciences, Blue Owl Healthcare Alternatives, Longitude Capital, OrbiMed, Logos Capital, Marshall Wace, Catalio Capital Administration, funds managed by abrdn Inc., and Digitalis Ventures.
The Massachusetts-based biotech firm is advancing using superior immunomodulators, together with its lead candidate AVD-104 for geographic atrophy secondary to age-related macular degeneration. Jeito stood out as the only real European fund among the many syndicate of institutional traders.
The funding will bolster Aviceda’s late-stage medical trials for AVD-104, a next-generation remedy demonstrating twin mechanisms of motion that focus on immune modulation and complement inhibition. Already, AVD-104 has proven promise in lowering lesion progress and enhancing visible perform in earlier trials.
This financing may even help Aviceda’s enlargement into different ophthalmic indications, because it anticipates pivotal 12-month endpoint knowledge in late 2025.
Dr Rafaèle Tordjman, MD, PhD, Founder and CEO of Jeito Capital stated: “Our funding in Aviceda Therapeutics completely illustrates our ambition to champion promising late-clinical stage biopharma with the potential to turn out to be world market leaders that can make a significant distinction in affected person lives. We’ve got been impressed by Aviceda’s new mechanism whose first optimistic outcomes characterize a brand new hope for sufferers. We stay up for beginning this new collaboration and bringing our European experience and world method to speed up this transformative remedy for sufferers with excessive unmet wants.”
Additional emphasising its experience in biopharma, Jeito led a €64.9 million Collection B financing spherical for Pennsylvania-based XyloCor Therapeutics, a clinical-stage firm on the forefront of gene remedy for heart problems.
Present institutional traders, together with EQT, Fountain Healthcare Companions, and Lumira Ventures, additionally participated within the spherical. Rachel Mears, Companion at Jeito Capital, may even be a part of XyloCor Board of Administrators.
This funding will help two Section 2 trials for its lead asset, XC001, geared toward treating refractory angina and as an adjunctive remedy in coronary artery bypass graft surgical procedure. The method, leveraging endocardial administration and focused angiogenesis, holds the potential to deal with the unmet wants of cardiovascular sufferers with restricted remedy choices.
Rachel Mears added: “We’re thrilled to help XyloCor because it advances its medical trials to judge XC001 as a possible remedy for sufferers fighting the burden of heart problems. The corporate has robust help from an skilled management workforce, world-class cardiologists and scientists and has made spectacular achievements in a short while in advancing its novel gene remedy method. We stay up for collaborating with the corporate because it progresses to the following steps in its medical programme.”
These investments spotlight Jeito’s strategic deal with high-impact therapeutic areas, together with ophthalmology and cardiology, in addition to following the latest acquisition of portfolio firm EyeBio by Merck & Co for as much as €2.8 billion.
Jeito’s twin presence in Europe and the US could place it to bridge these healthcare markets, leveraging its experience to foster cross-continental collaborations.